Article

Rapid and stable mobilization of fully functional spike-specific CD8+ T cells preceding a mature humoral response after SARS-CoV-2 mRNA vaccination

2021-05-11

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 spike mRNA vaccines mediate protection from severe disease as early as 10 days post prime vaccination, when specific antibodies are hardly detectable and still lack neutralizing activity. Vaccine-induced T cells, especially CD8+ T cells, may thus be the main mediators of protection at this early stage. The details of antigen-specific CD8+ T cell induction after prime/boost va...

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Literature Corpus work: c21dc2f6-4ca4-5a47-b714-b2c5f479fc16
DOI: 10.21203/rs.3.rs-505193/v1

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