Article

Epigenetic reprogramming restores metronidazole sensitivity in drug-resistant <i>Trichomonas vaginalis</i> parasites

2025-01-08

Abstract excerpt

<h4>ABSTRACT</h4> Resistance to antimicrobial drugs is a major global health challenge, yet the regulatory mechanisms underlying resistance phenotypes remain incompletely understood. In particular, whether epigenetic processes contribute to antimicrobial resistance in microbial eukaryotes is largely unexplored. Here, we show that epigenetic regulation plays a central role in modulating metronidazole resistance in...

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Literature Corpus work: c20cdb01-a1f9-5c41-8984-92b8177cb473
DOI: 10.1101/2025.01.07.631743

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