Article

Usp14 is required for spermatogenesis and ubiquitin stress responses in <i>Drosophila melanogaster</i>

2019-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Deubiquitinating (DUB) enzymes free covalently linked ubiquitins from ubiquitin-ubiquitin and ubiquitin-protein conjugates, and thereby maintain the equilibrium between free and conjugated ubiquitins and regulate ubiquitin-mediated cellular processes. The present genetic analyses of mutant phenotypes demonstrate that loss of Usp14 function results in male sterility, with defects in spermatid ind...

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Literature Corpus work: c1f7843b-22ec-58ab-b78b-c26242646448
DOI: 10.1101/724153

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