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Splice Variants of the SWR1-type Nucleosome Remodeling Factor Domino Have Distinct Functions during <i>Drosophila melanogaster</i> Oogenesis

2016-05-11

Abstract excerpt

SWR1-type nucleosome remodeling factors replace histone H2A by variants to endow chromatin locally with specialized functionality. In Drosophila melanogaster a single H2A variant, H2A.V, combines functions of mammalian H2A.Z and H2A.X in transcription regulation and DNA damage response. A major role in H2A.V incorporation for the only SWR1-like enzyme in flies, Domino, is assumed, but not well documented in vivo...

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Literature Corpus work
a654013b-7be7-5a6b-85af-9a1f92bc537b
DOI
10.1101/052746
Open publication

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Splice Variants of the SWR1-type Nucleosome Remodeling Factor Domino Have Distinct Functions during <i>Drosophila melanogaster</i> OogenesisDOI 10.1101/052746
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