Article
Development of a LAG-3 Immunohistochemistry Assay for Melanoma
2022-02-26
Abstract excerpt
<h4>Aims</h4> A robust immunohistochemistry (IHC) assay was developed to detect lymphocyte-activation gene 3 (LAG-3) expression by immune cells (ICs) in tumor tissues. LAG-3 is an immuno-oncology target with demonstrable clinical benefit, and there is a need for a standardized, well-characterized assay to measure its expression. This study aims to describe LAG-3 scoring criteria and present the specificity, sensi...
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Identifiers and source
- Literature Corpus work
- c1ce70ef-22c5-53b5-bd3e-26e75eef1198
- DOI
- 10.1101/2022.02.25.481964
