Article

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19

2020-03-23

Abstract excerpt

<h4>Introduction</h4> Coronavirus disease 2019 (COVID-19) is a respiratory infection caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). This virus uses the angiotensin converting enzyme II (ACE-2) as the cellular entry receptor to infect the lower respiratory tract. Because individuals with chronic obstructive pulmonary disease (COPD) are at increased risk of severe COVID-19, we determine...

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Literature Corpus work: c1bb7cf1-d8cd-5860-8cd4-0116e261b029
DOI: 10.1101/2020.03.18.20038455

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