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Article

Expression of the SARS-CoV-2 <i>ACE2</i> Receptor in the Human Airway Epithelium

20 May 2020

Abstract excerpt

Abstract Rationale Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first step in SARS-CoV-2 infection is binding of the virus to ACE2 (angiotensin-converting enzyme 2) on the airway epithelium. Objectives The objective was to gain insight into the expression of ACE2 in the human airway epithelium....

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PMID: 32432483
DOI: 10.1164/rccm.202003-0541oc

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