Article

Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects

2020-06-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Smokers and patients with chronic obstructive pulmonary disease (COPD) are at increased risk for severe Coronavirus Disease 2019 (COVID-19). <h4>Objectives</h4> We investigated the expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry receptor ACE2 and the protease TMPRSS2 in lung tissue from never smokers and smokers with and without COPD. <h4>Me...

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Literature Corpus work: 588f6e93-dd3d-50f2-9065-a239adf92b6a
DOI: 10.1101/2020.05.27.20114298

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