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The Neural Impact Score benchmarks drugs in Multi-Region Brain Organoids

2026-08-27

Abstract excerpt

Only about 10% of drugs that clear animal testing succeeds in humans, and central nervous system (CNS) programs carry an even steeper translational gap. Human-relevant NAMs are gaining global regulatory and funding support, creating an urgent need for interpretable preclinical systems that can generate comparable, decision-ready evidence across assays, models, and species. Yet the multimodal treatment-response dat...

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Literature Corpus work
c17bcb12-2d06-54c6-9d1c-3e46c5f07a4c
DOI
10.64898/2026.08.26.746777
Open publication

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The Neural Impact Score benchmarks drugs in Multi-Region Brain OrganoidsDOI 10.64898/2026.08.26.746777
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