Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database.

EBioMedicine - 1 Sept 2024

Chen Zhuohui, Wang Xiang, Teng Ziwei, Huang Jing, Mo Jianzhong, Qu Chunrun, Wu Yinghua, Liu Zhixiong, Liu Fangkun, Xia Kun

Abstract excerpt

BACKGROUND: Medications prescribed for chronic diseases can lead to short-term neuropsychiatric symptoms, but their long-term effects on brain structures and psychiatric conditions remain unclear. METHODS: We comprehensively analyzed the FDA Adverse Event Reporting System database and conducted drug target Mendelian Randomization (MR) studies on six categories of common drugs, 477 brain imaging-derived phenotypes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Databases, Factual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug-Related Side Effects and Adverse Reactions

Share to Gastrointestinal Microbiome

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Mental Disorders

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 39191171
DOI: 10.1016/j.ebiom.2024.105314
PMCID: PMC11400609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database.PMID 39191171Read ↗

Association of intestinal anti-inflammatory drug target genes with psychiatric Disorders: A Mendelian randomization study.Semantic proximity Read ↗

Pharmaceutical Repurposing Strategies for Metabolic Disorders: Insights from Mendelian Randomization StudiesSemantic proximity Read ↗

Mendelian Randomization Using the Druggable Genome Reveals Genetically Supported Drug Targets for Psychiatric Disorders.Semantic proximity Read ↗

Exploring glucagon-like peptide-1 receptor agonists as potential disease-modifying agent in psychiatric and neurodevelopmental conditions: evidence from a drug target Mendelian randomizationSemantic proximity Read ↗

The role of antipsychotics and other drugs on the development and progression of Neuroleptic Malignant SyndromeSemantic proximity Read ↗

Genome-wide Mendelian randomization identifies actionable novel drug targets for psychiatric disorders.Semantic proximity Read ↗

GLP1R gene expression is associated with metabolic and mental health effects in a phenome-wide drug repurposing and safety analysisSemantic proximity Read ↗

Discovery of Urinary Metabolite Biomarkers of Psychiatric Disorders Using Two-Sample Mendelian RandomizationSemantic proximity Read ↗

Genetics of Common Antipsychotic-Induced Adverse EffectsSemantic proximity Read ↗

Leveraging the Genetics of Psychiatric Disorders to Prioritize Potential Drug Targets and CompoundsSemantic proximity Read ↗

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.Semantic proximity Read ↗

Genome-wide Mendelian randomization and multi-omics integration identify drug targets for irritable bowel syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.