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Persistence and spread of fluconazole-resistant Candida parapsilosis clinical isolates associated with increased ERG11 copies in Qatar.

Microbial genomics - 1 Feb 2026

Zhang Zhu, Wang Yue, Ben Abid Fatma, Salah Husam, Al Ismail Khalil, Eldos Haneen, Samuel Bincy, Zhou Ruwen, Sundararaju Sathyavathi, Suleimen Mohammed, Wang Kun, Lee Bernett, Al Maslamani Muna, Sultan Ali A, Perez-Lopez Andres, Xu Jianping, Tsui Clement K M

Abstract excerpt

Candida parapsilosis is one of the most common species associated with candidemia infections globally. Recently, the emergence of fluconazole-resistant (FLU-R) C. parapsilosis has become a significant global public health concern. In this study, we investigated the genomic epidemiology and potential mechanisms of antifungal resistance among 51 hospital isolates in Qatar, of which 18 were FLU-R. Whole-genome SNP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41719169
DOI: 10.1099/mgen.0.001653
PMCID: PMC12927641

Genes

TAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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