Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Retrospective Molecular Epidemiology Study: Emergence and dissemination of Azole-Resistant Candida parapsilosis Sensu Stricto in Southern Brazil.

Mycopathologia - 7 Aug 2026

Rodrigues Luiza Souza, da Conceição Barbosa Sabrina, Chacon Ana Paula Santiago, Siqueira Adriele Celine, Bernardi Gisele Aparecida, Pillonetto Marcelo, Vicente Vania Aparecida, Arend Lavinia Nery Villa Stangler, Svidzinski Terezinha Inez Estivalet, Dalla-Costa Libera Maria

Abstract excerpt

Candida parapsilosis sensu stricto has emerged as a major cause of healthcare-associated candidemia, with increasing reports of fluconazole resistance worldwide. This resistance is most commonly associated with amino acid substitutions in Erg11p, particularly Y132F; however, regional variation in resistance mechanisms and clonal dissemination remains not fully understood. This study investigated the molecular...

Topics

Join the communities discussing this publication.

Antifungal Agents
Azoles
Brazil
Candidemia
Drug Resistance, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Epidemiology

Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 42567975
DOI: 10.1007/s11046-026-01095-0
PMCID: PMC13451485

Genes

TAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Retrospective Molecular Epidemiology Study: Emergence and dissemination of Azole-Resistant Candida parapsilosis Sensu Stricto in Southern Brazil.PMID 42567975Read ↗

Persistence and spread of fluconazole-resistant Candida parapsilosis clinical isolates associated with increased ERG11 copies in Qatar.Semantic proximity Read ↗

Species distribution, azole resistance and related molecular mechanisms in invasive Candida parapsilosis complex isolates: Increase in fluconazole resistance in 21 years.Semantic proximity Read ↗

First Report of Fluconazole-Resistant Candida parapsilosis Harbouring the G458S ERG11p Substitution in a Brazilian Hospital.Semantic proximity Read ↗

Molecular and Epidemiological Investigation of Fluconazole-resistant Candida parapsilosis —Georgia, United States, 2021Semantic proximity Read ↗

Fluconazole-resistant Candida parapsilosis genotypes from hospitals located in five Spanish cities and one in Italy: Description of azole-resistance profiles associated with the Y132F ERG11p substitution.Semantic proximity Read ↗

Genomic reconstruction of an azole-resistant <i>Candida parapsilosis</i> outbreak and the creation of a multilocus sequence typing scheme: a retrospective observational and genomic epidemiology studySemantic proximity Read ↗

Recent increase in fluconazole-nonsusceptible Candida parapsilosis in a global surveillance with the expansion of the Erg11 Y132F genotype and a rapid detection method for this alteration.Semantic proximity Read ↗

First Canadian report of transmission of fluconazole-resistant Candida parapsilosis within two hospital networks confirmed by genomic analysisSemantic proximity Read ↗

Emergence of multiple fluconazole-resistant Candida parapsilosis sensu stricto clones with persistence and transmission in ChinaSemantic proximity Read ↗

Azole Resistance and ERG11 Mutation in Clinical Isolates of Candida tropicalisSemantic proximity Read ↗

General hospital outbreak of invasive candidiasis due to azole-resistant Candida parapsilosis associated with an Erg11 Y132F mutation.Semantic proximity Read ↗

Determinants of fluconazole resistance and echinocandin tolerance in C. parapsilosis isolates causing a large clonal candidemia outbreak among COVID-19 patients in a Brazilian ICUSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.