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Article

Functional ADAM12 Variants Modulate Proteolytic Activity and Influence Metabolic Traits

2025-12-01

Abstract excerpt

<title>Abstract</title> <p> The high prevalence of insulin resistance and metabolic syndrome in Kuwait increases the risk of type 2 diabetes (T2D) and cardiovascular diseases development. Although the genetic contribution to insulin resistance and metabolic syndrome is established, the role of a disintegrin and metalloprotease 12 (ADAM12) in insulin resistance and T2D remains unclear. Our GWAS has identified fou...

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Literature Corpus work
c14520c6-266c-55df-bb06-28382749243d
DOI
10.21203/rs.3.rs-8138455/v1
Open publication

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Functional ADAM12 Variants Modulate Proteolytic Activity and Influence Metabolic TraitsDOI 10.21203/rs.3.rs-8138455/v1
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