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ADAMTS-12: Functions and Challenges for a Complex Metalloprotease

30 Apr 2021

Abstract excerpt

Nineteen members of the ADAMTS family of secreted zinc metalloproteinases are present in the human degradome. A wide range of different functions are being attributed to these enzymes and the number of their known substrates is considerably increasing in recent years. ADAMTSs can participate in processes such as fertility, inflammation, arthritis, neuronal and behavioral disorders, as well as cancer. Since its...

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PMID: 33996918
DOI: 10.3389/fmolb.2021.686763

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