Article

3-Mercaptopyruvate Sulfurtransferase (MPST) Regulates Mitochondrial Metabolism and Epithelial Differentiation in Neonatal Patient-derived Airway Cells

2025-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Early-life airway epithelial development relies on tightly coordinated mitochondrial metabolic programs, yet the pathways that govern normal epithelial maturation during this vulnerable developmental window remain poorly defined. Hyperoxia disrupts airway epithelial maturation, contributing to lung injury and airway remodeling in infants with bronchopulmonary dysplasia (BPD), underscoring the ne...

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Literature Corpus work: c1265c05-e419-5a66-b3b7-5b28ef434eea
DOI: 10.64898/2025.12.18.695204

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