Article

Senescence of stromal cells contributes to endometrium dysfunction and embryo implantation failure

2021-07-19

Abstract excerpt

Successful implantation requires two-sided interaction between genetically normal embryo and properly prepared endometrium. At the cellular level the latter means hormone-regulated differentiation of endometrial stromal cells (ESCs) into decidual ones that create appropriate microenvironment for invading embryo. Impaired decidualization is proved to mediate implantation failures. Here we elicited ESCs’ senescence...

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Literature Corpus work: c0e98801-8b81-57e6-9f97-dae375d87e8c
DOI: 10.1101/2021.07.19.452880

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