Article

The landscape of tolerated genetic variation in humans and primates

2023-05-02

Abstract excerpt

Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains largely incomplete. To systematically decipher the effects of human genetic variants, we obtained whole genome sequencing data for 809 individuals from 233 primate species, and identified 4.3 million common protein-altering variants with orthologs in human. We s...

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Literature Corpus work: 748fe551-3c4e-5e1d-944a-ba39b0d94650
DOI: 10.1101/2023.05.01.538953

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