Article

Plasticity as an Underlying Mechanism of Tumor Heterogeneity in Breast Cancer

2020-03-12

Abstract excerpt

Breast cancer shows plasticity in terms of classification. Upon drug treatment and metastasis some tumors switch to another subtype leading to loss of response to therapy. In this study, we ask the question which molecular subclasses of breast cancer are more switchable upon drug therapy and metastasis. We used in silico data to classify breast cancer tumors in PAM50 molecular classes before treatment and after tr...

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Literature Corpus work: c07f1598-b483-5f6a-823b-3cba94427e3f
DOI: 10.1101/2020.03.11.987511

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