Article

Perturbation and stability of PAM50 subtyping in population-based primary invasive breast cancer

2023-05-05

Abstract excerpt

<title>Abstract</title> <p>PAM50 gene expression subtypes represent a cornerstone in molecular classification of breast cancer and are included in risk prediction models to guide therapy. We aimed to illustrate the impact of included genes and biological processes on subtyping while considering a tumor’s underlying clinical subgroup defined by ER, PR and HER2 status. To do this we used a population-representative...

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Literature Corpus work: e2d5e06a-eaea-5ce0-b705-19449e928080
DOI: 10.21203/rs.3.rs-2832948/v1

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