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Predictive Performance and Clinical Application of PRS-15 for Venous Thromboembolism Risk in Chinese Orthopedic Patients: A Multicenter Prospective Case-Control Study

2026-02-19

Abstract excerpt

<title>Abstract</title> <p>Background Venous Thromboembolism (VTE) is influenced by clinical and genetic factors. The Caprini score is widely used but does not account for population-specific genetic susceptibility in Chinese individuals. We previously developed a Chinese-specific 15-variant polygenic risk score (PRS-15) for VTE; however, its clinical performance and added value when combined with the Caprini sc...

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Literature Corpus work: bfbe3cde-7115-5c96-8a17-0c7423e4e810
DOI: 10.21203/rs.3.rs-8190841/v1

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Predictive Performance and Clinical Application of PRS-15 for Venous Thromboembolism Risk in Chinese Orthopedic Patients: A Multicenter Prospective Case-Control StudyDOI 10.21203/rs.3.rs-8190841/v1Read

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