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Causal Association between Circulating Complement Components and Non-Viral Liver Diseases and Their Potential as Therapeutic Targets: An Integrated Analysis Based on Multi-omics Data

2023-07-20

Abstract excerpt

<h4>Backgrounds: </h4>: To evaluate the causal correlation between complement components and non-viral liver diseases and their potential use as druggable targets. Methods Two-sample Mendelian randomization (MR) was performed to assess the causal effect of circulating complement components on the risk of several non-viral liver diseases. Then complement-based protein-protein interaction network was constructed t...

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Literature Corpus work
bee65469-035a-5983-95cf-decf7fecef84
DOI
10.21203/rs.3.rs-3174913/v1
Open publication

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Causal Association between Circulating Complement Components and Non-Viral Liver Diseases and Their Potential as Therapeutic Targets: An Integrated Analysis Based on Multi-omics DataDOI 10.21203/rs.3.rs-3174913/v1
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