Article

A Hypothalamic Circuit Underlying the Dynamic Control of Social Homeostasis

2023-05-19

Abstract excerpt

<h4>Summary</h4> Social grouping increases survival in many species, including humans 1,2 . By contrast, social isolation generates an aversive state (loneliness) that motivates social seeking and heightens social interaction upon reunion 3-5 . The observed rebound in social interaction triggered by isolation suggests a homeostatic process underlying the control of social drive, similar to that observed for phy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: beb994e2-420e-5b59-a212-0e293e32b03c
DOI: 10.1101/2023.05.19.540391

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Hypothalamic Circuit Underlying the Dynamic Control of Social HomeostasisDOI 10.1101/2023.05.19.540391Read

Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent mannerSemantic proximity Read

Helping behavior is associated with increased affiliative behavior, activation of the prosocial brain network and elevated oxytocin receptor expression in the nucleus accumbensSemantic proximity Read

Separate BNST Microcircuits Targeted by Direct Versus Amygdala-Relayed Prefrontal Inputs Mediate Dissociable Phenotypes After Isolation.Semantic proximity Read

Social withdrawal: An initially adaptive behavior that becomes maladaptive when expressed excessivelySemantic proximity Read

Hormonal and Behavioral Consequences of Social Isolation and Loneliness: Neuroendocrine Mechanisms and Clinical ImplicationsSemantic proximity Read

Rodent models for mood disorders - understanding molecular changes by investigating social behavior.Semantic proximity Read

Sex differences in neural activity across amygdalo-striatal network during social behaviourSemantic proximity Read

Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationallySemantic proximity Read

Chronic Stress Induces Activity, Synaptic, and Transcriptional Remodeling of the Lateral Habenula Associated with Deficits in Motivated Behaviors.Semantic proximity Read

Lessons learned while evaluating how pairing aversive experiences with same or different sex social stimulus mice affects subsequent social engagementSemantic proximity Read

Postweaning social isolation and autism-like phenotype: A biochemical and behavioral comparative analysis.Semantic proximity Read

Optogenetic reactivation of prefrontal social memory trace mimics social buffering of fearSemantic proximity Read