Article

Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma

2020-12-11

Abstract excerpt

Hypoxanthine phosphoribosyl transferase ( HPRT1 ), as a salvage pathway enzyme, plays a crucial role in modulating the cell cycle and has been reported to be overexpressed in multiple cancers. Nevertheless, the relationship between the HPRT1 and Head and Neck Squamous Cell Carcinomas (HNSCC) has not been investigated so far. We first evaluated the expression of HPRT1 at transcriptomic and proteomic levels in tumor...

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Literature Corpus work: be90e88e-bad3-50ef-8877-3ad907483a4f
DOI: 10.1101/2020.12.10.20246991

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