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Article

High P4HA1 expression is an independent prognostic factor for poor overall survival and recurrent-free survival in head and neck squamous cell carcinoma.

Journal of clinical laboratory analysis - 1 Mar 2020

Li Qun, Shen Zhisen, Wu Zhenhua, Shen Yi, Deng Hongxia, Zhou Chongchang, Liu Huigao

Abstract excerpt

BACKGROUND: Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) plays a critical role in modulating the extracellular matrix and promoting tumor progression in various cancers. However, the association between P4HA1 and head and neck squamous cell carcinomas (HNSCC) has not been thoroughly elucidated to date. METHODS: P4HA1 mRNA and protein expression in cancer and normal tissues were analyzed using The Cancer Genome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

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Share to Squamous Cell Carcinoma of Head and Neck

Source

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Identifiers

PMID: 31782831
DOI: 10.1002/jcla.23107
PMCID: PMC7083458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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