Article
Transcriptomic Insights into Early Diagnosis of Doxorubicin-Induced Cardiotoxicity in a Rat Model
2025-04-07
Abstract excerpt
Doxorubicin is a member of the anthracycline class of chemotherapeutic agents and is among the most effective treatments available up to date. However, its clinical use is significantly limited by severe cardiotoxic effects. The purpose of this study is to investigate the transcriptomic alterations that occur in a rat model of doxorubicin-induced cardiotoxicity. Our results reveal significant dysregulations of car...
Topics
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- Cancer-related cognitive impairment studies
- Cardiovascular Function and Risk Factors
- Chemotherapy-induced cardiotoxicity and mitigation
- Chemotherapy-induced organ toxicity mitigation
- Circular RNAs in diseases
- GDF15 and Related Biomarkers
- Histone Deacetylase Inhibitors Research
- Takotsubo Cardiomyopathy and Associated Phenomena
Identifiers and source
- Literature Corpus work
- be5d05c5-5c2c-58ee-af62-5d19a22bb665
- DOI
- 10.1101/2025.04.01.646673
