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Review on the Role of Epigenetic Modifications in Doxorubicin-Induced Cardiotoxicity

7 May 2020

Abstract excerpt

Use of anthracyclines such as doxorubicin (DOX), for the treatment of cancer, is known to induce cardiotoxicity, begetting numerous evaluations of this adverse effect. This review emphasizes the mechanism of how consideration of DOX-induced cardiotoxicity is important for the development of cardioprotective agents. As DOX is involved in mitochondrial dysfunction, enzymes involved in epigenetic modifications that...

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PMID: 32457918
DOI: 10.3389/fcvm.2020.00056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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