Article

SWATH-MS for discovery of early biomarkers of drug-induced cardiotoxicity using an animal doxorubicin model

2025-08-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Clinical use of anthracyclines is limited by cumulative dose-dependent cardiotoxicity, though the mechanisms responsible for this are complex and incompletely understood. Existing biomarkers of anthracycline-related cardiotoxicity, such as troponin and NT-proBNP, lack sensitivity for the earliest stages of cardiotoxicity, therefore limiting scope to switch to...

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Literature Corpus work: 1f7b8d5c-611b-561c-ac96-8af9632d5dbe
DOI: 10.21203/rs.3.rs-7251224/v1

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