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Article

Population Prevalence, Penetrance, and Mortality for Genetically Confirmed MODY.

The Journal of clinical endocrinology and metabolism - 22 Apr 2026

Sharp Luke N, Colclough Kevin, Murray Leech Jacques, Cannon Stuart J, Laver Thomas W, Hattersley Andrew T, Weedon Michael N, Patel Kashyap A

Abstract excerpt

CONTEXT: Diagnosing maturity-onset diabetes of the young (MODY) is clinically important for treatment and prognosis. However, phenotype-based studies of MODY are prone to ascertainment bias, limiting accurate estimates of its population prevalence and phenotypic spectrum. OBJECTIVE: To apply a genotype-first approach to determine the population prevalence, penetrance, and all-cause mortality associated with MODY....

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41175096
DOI: 10.1210/clinem/dgaf599
PMCID: PMC13099198

Genes

GCK
HNF1A
NEUROD1
PDX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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