Article
Genetic Characterization of MODY in Iranian Families Using Multigenerational-Based Whole-Exome Sequencing Approach.
Journal of diabetes research - 1 Jan 2025
Sefid Fateme, Dehghan Tezerjani Masoud, Asadollahi Samira, Madani Seyed Ali, Pardal Tayebeh, Imani Maryam, Salmani Zahra, Rahmanian Masoud, Hozhabri Hossein, Kalantar Seyed Mehdi, Vahidi Mehrjardi Mohammad Yahya
Abstract excerpt
Background: Maturity-onset diabetes of the young (MODY), a common type of monogenic diabetes caused by a pathogenic variant in a single gene, is characterized by starting at an early age, autosomal dominant inheritance, and decreased secretion of insulin. Despite its clinical importance, its accurate diagnosis is challenging, and it is often misdiagnosed as other types of diabetes. Therefore, understanding the...
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