Article

Quercetin inhibits the growth of triple-negative breast cancer via the AKT1 pathway

2026-08-26

Abstract excerpt

<title>Abstract</title> <p>Triple-negative breast cancer (TNBC) is associated with a poor prognosis and lacks effective drugs. Quercetin (QUE), a dietary flavonoid compound, exhibits excellent anticancer activities. However, the effects and underlying mechanisms of QUE against TNBC remain unclear.This study aims to determine the role and regulation of AKT1 expression for QUE-mediated TNBC progression. Here, We fo...

Topics

Open a Topic to create a Post that cites this publication.

Uncategorized literature

Identifiers and source

Literature Corpus work: be51b14c-c00e-5d8d-9213-902b8f670f96
DOI: 10.21203/rs.3.rs-10738253/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 12 closest

Quercetin inhibits the growth of triple-negative breast cancer via the AKT1 pathwayDOI 10.21203/rs.3.rs-10738253/v1Read

Quercetin Suppresses TNBC Cell by Targeting ORM2Semantic proximity Read

Molecular Docking Appraisal of Dysphania ambrosioides Phytochemicals as Potential Inhibitor of a Key Triple-negative Breast Cancer Driver GeneSemantic proximity Read

Quercetin Suppresses TNBC Cell by Targeting ORM2Semantic proximity Read

Quercetin blocks the aggressive phenotype of triple-negative breast cancer by inhibiting IGF1/IGF1R-mediated EMT program.Semantic proximity Read

Discussion On The Mechanism of Que In The Treatment of Breast Neoplasms And Immune Prevention And TreatmentSemantic proximity Read

Curcumin suppresses metastasis of triple-negative breast cancer cells by modulating EMT signaling pathways: An integrated study of bioinformatics analysisSemantic proximity Read

STAMBPL1 promotes triple-negative breast cancer angiogenesis by upregulating the transcription of GRHL3/HIF1α/VEGFA via FOXO1Semantic proximity Read

Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review.Semantic proximity Read

Triptonide Effectively Inhibits Triple-Negative Breast Cancer Metastasis Through Concurrent Degradation Of Twist1 And Notch1 OncoproteinsSemantic proximity Read

TP53R175H mutation promotes breast cancer cell proliferation through CORO1A-P38 MAPK pathway regulation.Semantic proximity Read

Epigenetics of Triple-Negative Breast Cancer via Natural CompoundsSemantic proximity Read

CTPS1 Promotes Malignant Progression of Triple-Negative Breast Cancer With Transcriptional Activation By YBX1Semantic proximity Read