Article
TP53R175H mutation promotes breast cancer cell proliferation through CORO1A-P38 MAPK pathway regulation.
Biochemical pharmacology - 1 Mar 2024
Su Yali, Zhao Jiaxuan, Fu Haoran, Liu Zeliang, Du Panyan, Zheng Jianxia, Wu Jinghua, Zhang Jinghua
Abstract excerpt
Breast cancer is the most commonly diagnosed cancer in women. Among all types, triple-negative breast cancer is particularly challenging to cure because of its high recurrence rates and invasive and metastatic capacity. Although numerous studies have explored the role of TP53 mutations in cancer, there is a dearth of research regarding the correlation between TP53 mutations and breast cancer cell proliferation....
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