Article

Metformin Intervention Prevents Cardiac Dysfunction in a murine model of Adult Congenital Heart Disease

2018-08-21

Abstract excerpt

Congenital heart disease (CHD) is the most frequent birth defect worldwide and the number of adult patients with CHD, now referred to as ACHD, is increasing. However the mechanisms whereby ACHD predisposes patients to heart dysfunction are still unclear. ACHD is strongly associated with metabolic syndrome, but how ACHD interacts with poor modern lifestyle choices and other comorbidities, such as hypertension, obes...

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Literature Corpus work: be48fc0d-159a-5a7e-8326-7fe870e11e71
DOI: 10.1101/396416

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