Article

Integrated Mutational and Cytogenetic Analysis Identifies New Prognostic Subgroups in Chronic Lymphocytic Leukemia

2012-11-16

Abstract excerpt

Abstract Abstract 712 The identification of NOTCH1, SF3B1, MYD88 and BIRC3 genetic lesions in chronic lymphocytic leukemia (CLL) prompts a comprehensive and dynamic prognostic algorithm including gene mutations, chromosomal abnormalities, and their changes during clonal evolution. The study utilized both time-fixed (637 newly diagnosed CLL) and time-dependent (257 CLL provided with 524 sequential samples) approach...

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Chronic Lymphocytic Leukemia Research

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Literature Corpus work: be21aef2-899a-5599-a92b-c26188c8e803
DOI: 10.1182/blood.v120.21.712.712

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