Article
Impact of selection, mutation rate and genetic drift on human genetic variation.
Human molecular genetics - 15 Dec 2003
Sunyaev Shamil, Kondrashov Fyodor A, Bork Peer, Ramensky Vasily
Abstract excerpt
The accumulation of genome-wide information on single nucleotide polymorphisms in humans provides an unprecedented opportunity to detect the evolutionary forces responsible for heterogeneity of the level of genetic variability across loci. Previous studies have shown that history of recombination events has produced long haplotype blocks in the human genome, which contribute to this heterogeneity. Other factors,...
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