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Article

Pharmacotherapy exposure as a marker of disease complexity in bipolar disorder: Associations with clinical & genetic risk factors.

Psychiatry research - 1 May 2023

Sanchez Ruiz Jorge A, Coombes Brandon J, Pendegraft Richard S, Ozerdem Aysegul, McElroy Susan L, Cuellar-Barboza Alfredo B, Prieto Miguel L, Frye Mark A, Winham Stacey J, Biernacka Joanna M

Abstract excerpt

Individuals with bipolar disorder (BD) require chronic pharmacotherapy, typically including medication switches or polypharmacy due to persisting symptoms or intolerable side effects. Here, we quantified pharmacotherapy exposure (PE) of Mayo Clinic BD Biobank participants using the number of cross-sectional (at enrollment) and lifetime BD-specific medications and medication classes, to understand the relationship...

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PMID: 36965208
DOI: 10.1016/j.psychres.2023.115174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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