Article
Towards the clinical implementation of pharmacogenetics in bipolar disorder.
BMC medicine - 30 May 2014
Salloum Naji C, McCarthy Michael J, Leckband Susan G, Kelsoe John R
Abstract excerpt
BACKGROUND: Bipolar disorder (BD) is a psychiatric illness defined by pathological alterations between the mood states of mania and depression, causing disability, imposing healthcare costs and elevating the risk of suicide. Although effective treatments for BD exist, variability in outcomes leads to a large number of treatment failures, typically followed by a trial and error process of medication switches that...
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