Article
Loss of Nance-Horan Syndrome b ( <i>nhsb</i> ) prevents expansion growth of retinal progenitor cells by selective up-regulation of <i>Δ113p53</i>
2019-09-18
Abstract excerpt
The regulation of cell cycle progression and differentiation in retinal progenitor cells is a fundamental feature controlling organ size of the eye in vertebrates. Nance-Horan Syndrome (NHS) is a rare X-linked disorder caused by mutations in the NHS gene. Dysmorphic features of NHS include severe congenital cataracts, micropthalmia, facial dysmorphisms, and visual impairment. In this study we report an evolutiona...
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Identifiers and source
- Literature Corpus work
- bdec202b-80b6-51db-baff-0b752cf32774
- DOI
- 10.1101/775171
