Article

Resolving an underrepresented circulating tumor cell population in lung cancer enabled by Hexokinase 2 analysis

2020-04-29

Abstract excerpt

Unlike other epithelial cancer types, circulating tumor cells (CTCs) are less frequently detected in the peripheral blood of non-small cell lung cancer (NSCLC) patients using epithelial marker-based detection approaches, despite the aggressive nature of NSCLC. Here we demonstrate hexokinase-2 (HK2) as a metabolic function-associated marker for detection of CTCs, with significantly improved detection rates and high...

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Literature Corpus work: bd8cffd1-94d4-57b1-8178-46073b5f02e1
DOI: 10.1101/2020.04.27.064345

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