Article

Complex intra-host SARS-CoV-2 evolution following monoclonal antibody pre-exposure prophylaxis

2026-07-17

Abstract excerpt

<h4>Background: </h4> Monoclonal antibodies have emerged as a prophylactic strategy to prevent symptomatic SARS-CoV-2 infection in immunocompromised individuals. However, the evolutionary and clinical implications of breakthrough infections under this regime remain unclear. <h4>Methods:</h4> A male in their 80s with a haematological/oncological diagnosis received a 2000 mg intravenous infusion of sotrovimab in Mar...

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Literature Corpus work: bd423154-0951-58c8-9e80-d8d5177b7535
DOI: 10.64898/2026.07.14.26356329

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