Evaluating bacterial and functional diversity of human gut microbiota by complementary metagenomics and metatranscriptomics

Abstract excerpt

<h4>ABSTRACT</h4> It is well accepted that dysbiosis of microbiota is associated with disease; however, the biological mechanisms that promote susceptibility or resilience to disease remain elusive. One of the major limitations of previous microbiome studies has been the lack of complementary metatranscriptomic (functional) data to complement the interpretation of metagenomics (bacterial abundance). The purpose o...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Food Security and Health in Diverse Populations
• Gut microbiota and health
• Helicobacter pylori-related gastroenterology studies
• Nutrition, Genetics, and Disease
• Probiotics and Fermented Foods
• Tryptophan and brain disorders

Identifiers and source

Literature Corpus work

0ed834ce-7105-5872-b62a-956fc8ef3d41

DOI

10.1101/363200