Article

RUNX1 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS-induced ARDS in rat via NF-κ B pathway

2023-04-26

Abstract excerpt

<h4>Background: </h4> Previous studies have confirmed that acute respiratory distress syndrome (ARDS) is characterized by alveolar hypercoagulation and fibrinolytic inhibition. However, the underlying mechanism remains unclear. Runt-related transcription factor 1 (RUNX1) is a transcription factor expressed in various organs, including lung tissue, and is involved in multiple pathophysiological processes such as in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bce79125-98ea-5692-a66f-6235e1a624ab
DOI: 10.21203/rs.3.rs-2847332/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

RUNX1 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS-induced ARDS in rat via NF-κ B pathwayDOI 10.21203/rs.3.rs-2847332/v1Read

RUNX1: A Regulator of NF-κB Signaling in Pulmonary DiseasesSemantic proximity Read

LncRNA HOTAIR Increases Inflammatory Responses by Activating NF-κB Pathway in LPS-Induced Acute Lung InjurySemantic proximity Read

rhMFGE8 Attenuates Endothelial-to-Mesenchymal Transition in Acute Lung Injury Induced by Lipopolysaccharide Through the BMP/Smad1/4/5/Snail Signalling PathwaySemantic proximity Read

NFKB1/NR3C1-MAPK4 axis regulates the pathology of acute lung injurySemantic proximity Read

siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury.Semantic proximity Read

MRTF-A mediates LPS-induced pro-inflammatory transcription by interacting with the COMPASS complexSemantic proximity Read

Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targetsSemantic proximity Read

LncRNA analysis of lung tissues after hUC-MSCs and FTY720 treatment of lipopolysaccharide-induced acute lung injury in mouse modelsSemantic proximity Read

Preparation of a miR-155-activating Nucleic Acid Nanoflower to Study the Molecular Mechanism of miR-155 in InflammationSemantic proximity Read

Genome-wide analysis of DNA methylation in rat lungs with lipopolysaccharide-induced acute lung injurySemantic proximity Read

Identification of Different Proteins Binding to Na, K-ATPase α1 in LPS-Induced ARDS Cell Model by Proteomic AnalysisSemantic proximity Read

Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis.Semantic proximity Read