Article

Self-reported health history from 70,724 individuals reveals novel HLA associations with allergy and other frequently underreported conditions

2026-02-19

Abstract excerpt

<h4>Background</h4> Variation in the HLA loci, located on human chromosome 6p, has been associated with hundreds of diseases and conditions. However, high levels of polymorphism that characterize the HLA system, coupled with generally modest effect sizes for most phenotypes, necessitate relatively large sample sizes to power association studies; meanwhile, high resolution HLA genotyping remains relatively resou...

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Literature Corpus work: bce68b31-fa70-5c4a-977d-c5254f8567f5
DOI: 10.64898/2026.02.18.26346586

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