Article

The conserved QTQTX motif in the SARS-CoV-2 spike protein is dispensable for cleavage and lung cell entry of the emerging variant BA.3.2

2026-05-07

Abstract excerpt

<h4>ABSTRACT</h4> The furin motif in the SARS-CoV-2 spike (S) protein is important for lung cell entry. It is embedded in an extended loop structure and preceded by a highly conserved QTQTX motif that is required for efficient furin cleavage of the SARS-CoV-2 WA-1 S protein. BA.3.2 is an emerging SARS-CoV-2 saltation variant that is spreading globally in April 2026 and encodes for a highly mutated S protein. Here...

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Literature Corpus work: bcd91991-04ff-58ad-bcda-6e231aa02c27
DOI: 10.64898/2026.05.04.722688

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