Article

Induced pluripotent stem cell-derived human macrophages as an infection model for <i>Leishmania donovani</i>

2023-08-02

Abstract excerpt

The parasite Leishmania donovani is one of the species causing visceral leishmaniasis in humans, a deadly infection claiming up to 40,000 lives each year. The current drugs for leishmaniasis treatment have severe drawbacks and there is an urgent need to find new anti-leishmanial compounds. However, the search for drug candidates is complicated by the intracellular lifestyle of Leishmania . Here, we investigate t...

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Literature Corpus work: bcc6093a-0946-5c7d-a65f-765841b252ac
DOI: 10.1101/2023.07.31.551225

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