Article

2’, 3’, 4’-trihydroxychalcone is an Estrogen Receptor Ligand Which Modulates the Activity of 17β-estradiol

2019-04-13

Abstract excerpt

<h4>ABSTRACT</h4> Menopausal hormone therapy (MHT) reduces the risk of osteoporosis, fractures, obesity and diabetes, but long-term MHT increases risk of other diseases. Safe long-term MHT that exploits its benefits and abrogates its adverse effects requires a new approach. Here we demonstrate that 2’, 3’, 4’-trihydroxychalcone (CC7) acts as an estrogen receptor alpha (ERα) ligand that may improve the safety prof...

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Literature Corpus work: bcbc2c9f-eeac-5211-94d5-3f8e30b0157d
DOI: 10.1101/607275

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