Article

Structure-based modeling of SARS-CoV-2 peptide/HLA-A02 antigens

2020-03-27

Abstract excerpt

<h4>ABSTRACT</h4> As a first step toward the development of diagnostic and therapeutic tools to fight the Coronavirus disease (COVID-19), it is important to characterize CD8+ T cell epitopes in the SARS-CoV-2 peptidome that can trigger adaptive immune responses. Here, we use RosettaMHC, a comparative modeling approach which leverages existing high-resolution X-ray structures from peptide/MHC complexes available i...

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Literature Corpus work: bc864915-ac4a-593d-981d-2ea2f1e4b46b
DOI: 10.1101/2020.03.23.004176

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