Article

Generating synthetic tau-PET scans in Alzheimer’s disease from MRI, blood biomarkers and demographics with deep learning

2026-05-07

Abstract excerpt

Tau protein aggregation in the brain is a hallmark of Alzheimer’s disease (AD). Positron emission tomography (PET) is the only in vivo method to visualize tau pathology and estimate both its burden and regional distribution, but the use of tau-PET is constrained by high cost and limited accessibility. Here, we develop a deep learning model to synthesize tau-PET scans from more accessible data: structural magnetic...

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Literature Corpus work: bc7f6672-7862-5083-93ef-fc8806a1422f
DOI: 10.64898/2026.05.06.26352540

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