Article

Deep Learning for Alzheimer’s Disease: Mapping Large-scale Histological Tau Protein for Neuroimaging Biomarker Validation

2019-07-11

Abstract excerpt

Deposits of abnormal tau protein inclusions in the brain are a pathological hallmark of Alzheimer’s disease (AD), and are the best predictor of neuronal loss and clinical decline, but have been limited to postmortem assessment. Imaging-based biomarkers to detect tau deposits in vivo could leverage AD diagnosis and monitoring beginning in pre-symptomatic disease stages. Several PET tau tracers are available for re...

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Literature Corpus work: 91fa1b12-da7d-5e79-bbe9-98726cb90acf
DOI: 10.1101/698902

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