Article

Neuropathologically validated MRI to tau PET synthesis via Covariate-modulated attention networks

2025-12-27

Abstract excerpt

Tau PET is a powerful tool to assess tau pathology in vivo; however, in comparison to MRI, its development is more recent, is rarely available at scale, and substantially more difficult to acquire. Here, we present Covariate-Modulated Attention UNet (CoMA-UNet) to synthesize subject-specific 3D tau PET from T1 MRI while incorporating in the synthesis procedure readily available covariates. Across six external vali...

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Literature Corpus work: a11b7181-c041-508b-bc9f-0e5a9e58e8c3
DOI: 10.64898/2025.12.27.696668

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