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Exosomal Proteomic Signatures Correlate With Drug Resistance and Carboplatin Treatment Outcome in a Spontaneous Model of Canine Osteosarcoma

2021-02-25

Abstract excerpt

<title>Abstract</title> <p>BackgroundOsteosarcoma patients often experience poor outcomes despite chemotherapy treatment, likely due in part to various mechanisms of tumor cell innate and/or acquired drug resistance. Exosomes, microvesicles secreted by cells, have been shown to play a role in drug resistance, but a comprehensive protein signature relating to osteosarcoma carboplatin resistance has not been fully...

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Literature Corpus work
bc5adf3b-b391-5ff9-a399-83ac7efc032c
DOI
10.21203/rs.3.rs-240444/v1
Open publication

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Exosomal Proteomic Signatures Correlate With Drug Resistance and Carboplatin Treatment Outcome in a Spontaneous Model of Canine OsteosarcomaDOI 10.21203/rs.3.rs-240444/v1
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